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Test Code C4 Complement C4, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Secondary ID

800020

Useful For

Investigating an undetectable total complement

 

Confirming hereditary angioedema (with low C1 inhibitor)

 

Assessing disease activity in systemic lupus erythematosus, proliferative glomerulonephritis, rheumatoid arthritis, and autoimmune hemolytic anemia

Method Name

Nephelometry

Reporting Name

Complement C4, S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis OK
Gross lipemia Reject
Gross icterus OK

Reference Values

14-40 mg/dL

Performing Laboratory

Mayo Clinic Laboratories in Florida

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86160

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C4 Complement C4, S 4498-2

 

Result ID Test Result Name Result LOINC Value
C4 Complement C4, S 4498-2

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Day(s) Performed

Monday through Friday, Sunday

Report Available

1 to 3 days