Sign in →

Test Code FACTOR V (LEIDEN) MUTATION FACTOR V (LEIDEN) MUTATION

Department

Molecular

Group Components

FACTOR V LEIDEN

Specimen Type

Whole Blood

Container

Sodium citrate 3.2% (light blue-top) or EDTA (lavender-top)

Standard Volume

5.0ml

Minimum Volume

1.0ml

Pediatric Volume

N/A

Method

Real-time Polymerase Chain Reaction (PCR)

Ship Temperature

Refrigerated

Stability Room Temp

24 hours

Stability Refrigerated

15 days

CPT Code

81241

Days Test Set Up

Monday through Sunday

DEX code

ZB4IL

Clinical Information

This test is intended to provide results for Factor V Leiden (G1691A) mutations as an aid in the diagnosis in individuals with suspected thrombophilia. Factor V Leiden (G1691A) refers to the G to A transition at nucleotide position 1691 of the Factor V gene, resulting in the substitution of the amino acid arginine by glutamine in the Factor V protein, causing resistance to cleavage by Activated Protein C (APC).