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Test Code IMFX Immunofixation, Serum


Specimen Required


Only orderable as part of a profile. For more information see MPSS / Monoclonal Protein Study, Serum.

 

Patient Preparation: Fasting preferred but not required

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Secondary ID

800306

Useful For

Aids in diagnosis of monoclonal gammopathies when used in conjunction with urine monoclonal studies

 

Identification and isotyping of monoclonal immunoglobulin heavy and light chains

 

Documentation of complete response to therapy

Method Name

Only orderable as part of a profile. For more information see MPSS / Monoclonal Protein Study, Serum.

 

Immunofixation

Reporting Name

Immunofixation

Specimen Type

Serum

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reference Values

Only orderable as part of a profile. For more information see MPSS / Monoclonal Protein Study, Serum.

 

Immunofixation: No monoclonal protein detected

Flag, Immunofixation: Negative

Performing Laboratory

Mayo Clinic Laboratories in Florida

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86334

LOINC Code Information

Test ID Test Order Name Order LOINC Value
IMFX Immunofixation 74665-1

 

Result ID Test Result Name Result LOINC Value
81653 Immunofixation 74665-1
606977 Flag, Immunofixation No LOINC Needed

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
Other 3 freeze/thaw cycles

Day(s) Performed

Monday through Friday

Report Available

3 to 7 days

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
IFXED Immunofixation Delta and Epsilon, S Yes No

Testing Algorithm

If a monoclonal light chain is detected in the absence of an associated monoclonal heavy chain, immunofixation electrophoresis specific for delta and epsilon chains is performed, if not previously performed, or at the discretion of the laboratory director reviewing the case.